TIMI Frame Count and Adverse Events in Women with No Obstructive Coronary Disease: A Pilot Study from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE)

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TIMI Frame Count and Adverse Events in Women with No Obstructive Coronary Disease: A Pilot Study from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE)

BACKGROUND TIMI frame count (TFC) predicts outcomes in patients with obstructive coronary artery disease (CAD); it remains unclear whether TFC predicts outcomes in patients without obstructive CAD. METHODS TFC was determined in a sample of women with no obstructive CAD enrolled in the Women's Ischemia Syndrome Evaluation (WISE) study. Because TFC is known to be higher in the left anterior des...

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Persistent chest pain predicts cardiovascular events in women without obstructive coronary artery disease: results from the NIH-NHLBI-sponsored Women's Ischaemia Syndrome Evaluation (WISE) study.

AIMS Women with chest pain but without obstructive coronary artery disease (CAD) are considered at low risk for cardiovascular (CV) events, but half continue to experience debilitating chest pain over many years. This study compared CV outcomes in women with persistent chest pain (PChP) vs. those without PChP. METHODS AND RESULTS We studied 673 Women's Ischaemia Syndrome Evaluation (WISE) par...

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Inflammatory biomarkers as predictors of heart failure in women without obstructive coronary artery disease: A report from the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation (WISE)

BACKGROUND Women with signs and symptoms of ischemia, no obstructive coronary artery disease (CAD) and preserved left ventricular ejection fraction (EF) often have diastolic dysfunction and experience elevated rates of major adverse cardiac events (MACE), including heart failure (HF) hospitalization with preserved ejection fraction (HFpEF). We evaluated the predictive value of inflammatory biom...

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Five-year stroke rate in women with signs and symptoms of ischemia undergoing coronary angiography: a retrospective study from the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation (WISE)

A Haftbaradaran, M Zaya, PK Mehta, C Shufelt, G Lentz, Shivani Dhawan, J Petersen, E Handberg, BD Johnson, CJ Pepine, D Leach, S Long and CN Bairey Merz Barbra Streisand Women’s Heart Center, Cedars-Sinai Heart Institute, Los Angeles, CA 90048, USA University of Florida, Gainesville, FL, USA University of Pittsburgh, Pittsburgh, PA, USA Corresponding author: C Noel Bairey Merz. Email: noel.bair...

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Tissue characterization with native T1 mapping in suspected coronary microvascular dysfunction and no obstructive coronary artery disease: results from the NHLBI-sponsored WISE study

Background About half of all women who present with symptoms of ischemic heart disease have no obstructive coronary artery disease. These women are often deemed “low-risk” patients according to conventional cardiology wisdom. The Women’s Ischemia Syndrome Evaluation (WISE) studies have demonstrated suspected coronary microvascular dysfunction (CMD) in women with persistent angina, evidence of i...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2014

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0096630